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Please use this identifier to cite or link to this item: http://hdl.handle.net/10926/1988

Title: Evolutionary insights from bat trypanosomes: morphological, developmental and phylogenetic evidence of a new species, trypanosoma (schizotrypanum) erneyi sp. nov., in african bats closely related to trypanosoma (schizotrypanum) cruzi and Aallied species
Authors: Lima, Luciana
Silva, Flávia Maia da
Neves, Luis
Attias, Márcia
Takata, Carmen Silva de Almeida
Campaner, Marta
Souza, Wanderley de
Hamilton, Patrick B.
Teixeira, Marta Maria Geraldes
Keywords: África
Morcego
Chiroptera
Evolução
Filogenia
Trypanossoma
Issue Date: 2012
Citation: LIMA, Luciana et al. Evolutionary insights from bat trypanosomes: morphological, developmental and phylogenetic evidence of a new species, trypanosoma (schizotrypanum) erneyi sp. nov., in african bats closely related to trypanosoma (schizotrypanum) cruzi and Aallied species. Protist, v.163, n.6, p. 856-872, 2012.
Abstract: Parasites of the genus Trypanosoma are common in bats and those of the subgenus Schizotrypanum are restricted to bats throughout the world, with the exception of Trypanosoma (Schizotrypanum) cruzi that also infects other mammals and is restricted to the American Continent. We have characterized try- panosome isolates from Molossidae bats captured in Mozambique, Africa. Morphology and behaviour in culture, supported by phylogenetic inferences using SSU (small subunit) rRNA, gGAPDH (glycoso- mal glyceraldehyde 3-phosphate dehydrogenase) and Cyt b (cytochrome b) genes, allowed to classify the isolates as a new Schizotrypanum species named Trypanosoma (Schizotrypanum) erneyi sp. nov. This is the first report of a Schizotrypanum species from African bats cultured, characterized morphologically and biologically, and positioned in phylogenetic trees. The unprecedented finding of a new species of the subgenus Schizotrypanum from Africa that is closest related to the America-restricted Trypanosoma (Schizotrypanum) cruzi marinkellei and T. cruzi provides new insights into the origin and evolutionary history of T. cruzi and closely related bat trypanosomes. Altogether, data from our study support the hypothesis of an ancestor trypanosome parasite of bats evolving to infect other mammals, even humans, and adapted to transmission by triatomine bugs in the evolutionary history of T. cruzi in the New World.
Description: 17 p. : il., tab.
Document type: Artigo / Article
Unit: DIPRO - Diretoria de Programa
Appears in Collections:DIMAV | Artigos publicados em periódicos internacionais

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